Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer

Hypoxia and NOTCH signaling have been reported to be associated with the self-renewal and drug resistance of cancer stem cells (CSCs). However, the molecular mechanisms by which hypoxia and NOTCH signaling stimulate the self-renewal and drug resistance of ovarian CSCs are poorly understood. In the p...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Seo, Eun Jin, Kim, Dae Kyoung, Jang, Il Ho, Choi, Eun Jung, Shin, Sang Hun, Lee, Su In, Kwon, Sang-Mo, Kim, Ki-Hyung, Suh, Dong-Soo, Kim, Jae Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342441/
https://ncbi.nlm.nih.gov/pubmed/27489349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10954
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