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Ranking novel cancer driving synthetic lethal gene pairs using TCGA data
Synthetic lethality (SL) has emerged as a promising approach to cancer therapy. In contrast to the costly and labour-intensive genome-wide siRNA or CRISPR-based human cell line screening approaches, computational approaches to prioritize potential synthetic lethality pairs for further experimental v...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342422/ https://ncbi.nlm.nih.gov/pubmed/27438146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10536 |
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