Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma

Hepatitis B virus (HBV) X protein (HBx), a trans-regulator, is frequently expressed in truncated form without carboxyl-terminus in hepatocellular carcinoma (HCC), but its functional mechanisms are not fully defined. In this report, we investigated frequency of this natural HBx mutant in HCCs and its...

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Publicat a:Oncotarget
Autors principals: Li, Weihua, Li, Man, Liao, Dongjiang, Lu, Xinpeng, Gu, Xia, Zhang, Qianqian, Zhang, Zhixiang, Li, Hui
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342405/
https://ncbi.nlm.nih.gov/pubmed/27391153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10399
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