Dose-dependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer's disease

In humans, brain-derived neurotrophic factor (BDNF) has been shown to play a pivotal role in neurocognition, and its gene contains a functional polymorphism (Val66Met) that may explain individual differences in brain volume and memory-related activity. In this study, we enrolled 186 Alzheimer's...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Lin, Pin-Hsuan, Tsai, Shih-Jen, Huang, Chi-Wei, Mu-En, Liu, Hsu, Shih-Wei, Lee, Chen-Chang, Chen, Nai-Ching, Chang, Ya-Ting, Lan, Min-Yu, Chang, Chiung-Chih
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Gerotarget (Focus on Aging)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342335/
https://ncbi.nlm.nih.gov/pubmed/27494844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11027
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