Spc24 is required for meiotic kinetochore-microtubule attachment and production of euploid eggs

Mammalian oocytes are particularly error prone in chromosome segregation during two successive meiotic divisions. The proper kinetochore-microtubule attachment is a prerequisite for faithful chromosome segregation during meiosis. Here, we report that Spc24 localizes at the kinetochores during mouse...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zhang, Teng, Zhou, Yang, Wang, Hong-Hui, Meng, Tie-Gang, Guo, Lei, Ma, Xue-Shan, Shen, Wei, Schatten, Heide, Sun, Qing-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342138/
https://ncbi.nlm.nih.gov/pubmed/27713128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12453
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