Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy

Patient-derived xenograft (PDX) mouse models of cancer are emerging as an important component of personalized precision cancer therapy. However, most models currently offered to patients have their tumors subcutaneously-transplanted in immunodeficient mice, which rarely metastasize. In contrast, ort...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Zhang, Nan, Murakami, Takashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342112/
https://ncbi.nlm.nih.gov/pubmed/27765934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12322
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items