FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

Several fibroblast growth factor (FGF) isoforms act to stimulate epithelial-mesenchymal transition (EMT) during cancer progression. FGF4 and FGF7 are two ligands of FGF receptor 2 (FGFR2). Using two lung adenocarcinoma (ADC) cell lines, A549 and H1299, we showed that FGF4, but not FGF7, altered cell...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qi, Lisha, Song, Wangzhao, Li, Lingmei, Cao, Lu, Yu, Yue, Song, Chunmin, Wang, Yalei, Zhang, Fei, Li, Yang, Zhang, Bin, Cao, Wenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342032/
https://ncbi.nlm.nih.gov/pubmed/27677589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12187
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