Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

BACKROUND: Steatohepatitis (SH)-associated liver carcinogenesis is an increasingly important issue in clinical medicine. SH is morphologically characterized by steatosis, hepatocyte injury, ballooning, hepatocytic cytoplasmic inclusions termed Mallory-Denk bodies (MDBs), inflammation and fibrosis. R...

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Publicado en:Oncotarget
Main Authors: Bettermann, Kira, Mehta, Anita Kuldeep, Hofer, Eva M., Wohlrab, Christina, Golob-Schwarzl, Nicole, Svendova, Vendula, Schimek, Michael G., Stumptner, Cornelia, Thüringer, Andrea, Speicher, Michael R., Lackner, Carolin, Zatloukal, Kurt, Denk, Helmut, Haybaeck, Johannes
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341981/
https://ncbi.nlm.nih.gov/pubmed/27689336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12325
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