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Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization

Tumor microenvironment has been described to play a key role in tumor growth, progression, and metastasis. Macrophages are a major cellular constituent of the tumor stroma, and particularly tumor associated macrophages (TAMs or M2-like macrophages) exert important immunosuppressive activity and a pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Jiménez-García, Lidia, Herranz, Sandra, Higueras, María Angeles, Luque, Alfonso, Hortelano, Sonsoles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341841/
https://ncbi.nlm.nih.gov/pubmed/27572316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11652
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