New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status

We synthesized, characterized and tested in a panel of cancer cell lines, nine new bipyridine gold(III) dithiocarbamate-containing complexes. In vitro studies demonstrated that compounds 1, 2, 4, 5, 7 and 8 were the most cytotoxic in prostate, breast, ovarian cancer cell lines and in Hodgkin lymphom...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Altaf, Muhammad, Monim-ul-Mehboob, Muhammad, Kawde, Abdel-Nasser, Corona, Giuseppe, Larcher, Roberto, Ogasawara, Marcia, Casagrande, Naike, Celegato, Marta, Borghese, Cinzia, Siddik, Zahid H., Aldinucci, Donatella, Isab, Anvarhusein A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341752/
https://ncbi.nlm.nih.gov/pubmed/27888799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13448
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