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Many roads to symmetry breaking: molecular mechanisms and theoretical models of yeast cell polarity

Mathematical modeling has been instrumental in identifying common principles of cell polarity across diverse systems. These principles include positive feedback loops that are required to destabilize a spatially uniform state of the cell. The conserved small G-protein Cdc42 is a master regulator of...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Goryachev, Andrew B., Leda, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341721/
https://ncbi.nlm.nih.gov/pubmed/28137950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0739
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