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Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock

BACKGROUND: Acute kidney injury (AKI) is a multifactorial syndrome, but knowledge about its pathophysiology and possible genetic background is limited. Recently the first hypothesis-free genetic association studies have been published to explore individual susceptibility to AKI. We aimed to replicat...

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Pubblicato in:Crit Care
Autori principali: Vilander, Laura M., Kaunisto, Mari A., Vaara, Suvi T., Pettilä, Ville
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341446/
https://ncbi.nlm.nih.gov/pubmed/28270177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-017-1631-3
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