Characterization of the HLA-DRβ1 third hypervariable region amino acid sequence according to charge and parental inheritance in systemic sclerosis

BACKGROUND: Specific HLA class II alleles are associated with systemic sclerosis (SSc) risk, clinical characteristics, and autoantibodies. HLA nomenclature initially developed with antibodies as typing reagents defining DRB1 allele groups. However, alleles from different DRB1 allele groups encode th...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Gentil, Coline A., Gammill, Hilary S., Luu, Christine T., Mayes, Maureen D., Furst, Dan E., Nelson, J. Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341397/
https://ncbi.nlm.nih.gov/pubmed/28270189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1253-9
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