Exploring Deformable Particles in Vascular-Targeted Drug Delivery: Softer is Only Sometimes Better

The ability of vascular-targeted drug carriers (VTCs) to localize and bind to a targeted, diseased endothelium determines their overall clinical utility. Here, we investigate how particle modulus and size determine adhesion of VTCs to the vascular wall under physiological blood flow conditions. In g...

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Bibliografiske detaljer
Udgivet i:Biomaterials
Main Authors: Fish, Margaret B., Fromen, Catherine A., Lopez-Cazares, Genesis, Golinski, Alexander W., Scott, Timothy F., Adili, Reheman, Holinstat, Michael, Eniola-Adefeso, Omolola
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341378/
https://ncbi.nlm.nih.gov/pubmed/28209527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.02.002
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