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Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer

Increased collagen expression in tumors is associated with increased risk of metastasis, and triple-negative breast cancer (TNBC) has the highest propensity to develop distant metastases when there is evidence of central fibrosis. Transforming growth factor-β (TGF-β) ligands regulated by cancer-asso...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Takai, Ken, Le, Annie, Weaver, Valerie M., Werb, Zena
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341254/
https://ncbi.nlm.nih.gov/pubmed/27756881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12658
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