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Protease‐activated receptor 4: from structure to function and back again

Protease‐activated receptors are a family of four GPCRs (PAR1–PAR4) with a number of unique attributes. Nearly two and a half decades after the discovery of the first PAR, an antagonist targeting this receptor has been approved for human use. The first‐in‐class PAR1 antagonist, vorapaxar, was approv...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: French, Shauna L, Hamilton, Justin R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341247/
https://ncbi.nlm.nih.gov/pubmed/26844674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13455
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