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Protease‐activated receptor 4: from structure to function and back again
Protease‐activated receptors are a family of four GPCRs (PAR1–PAR4) with a number of unique attributes. Nearly two and a half decades after the discovery of the first PAR, an antagonist targeting this receptor has been approved for human use. The first‐in‐class PAR1 antagonist, vorapaxar, was approv...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341247/ https://ncbi.nlm.nih.gov/pubmed/26844674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13455 |
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