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The effects of Y-27632 on pial microvessels during global brain ischemia and reperfusion in rabbits
BACKGROUND: Global brain ischemia-reperfusion during propofol anesthesia provokes persistent cerebral pial constriction. Constriction is likely mediated by Rho-kinase. Cerebral vasoconstriction possibly exacerbates ischemic brain injury. Because Y-27632 is a potent Rho-kinase inhibitor, it should be...
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| Published in: | BMC Anesthesiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341179/ https://ncbi.nlm.nih.gov/pubmed/28270098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-017-0331-5 |
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