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Parkin in cancer: Mitophagy-related/unrelated tasks

Dysfunctional mitochondria may produce excessive reactive oxygen species, thus inducing DNA damage, which may be oncogenic if not repaired. As a major role of the PINK1-Parkin pathway involves selective autophagic clearance of damaged mitochondria via a process termed mitophagy, Parkin-mediated mito...

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Detalles Bibliográficos
Publicado en:World J Hepatol
Main Authors: Eid, Nabil, Kondo, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340990/
https://ncbi.nlm.nih.gov/pubmed/28321271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v9.i7.349
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