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A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing

Splicing of precursor mRNA occurs via two consecutive steps of transesterification reaction; both require ATP and several proteins. Despite the energy requirement in the catalytic phase, incubation of the purified spliceosome under proper ionic conditions can elicit competitive reversible transester...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Tseng, Chi-Kang, Chung, Che-Sheng, Chen, Hsin-Chou, Cheng, Soo-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340917/
https://ncbi.nlm.nih.gov/pubmed/28057857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.059204.116
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