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A role for cerebellum in the hereditary dystonia DYT1

DYT1 is a debilitating movement disorder caused by loss-of-function mutations in torsinA. How these mutations cause dystonia remains unknown. Mouse models which have embryonically targeted torsinA have failed to recapitulate the dystonia seen in patients, possibly due to differential developmental c...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fremont, Rachel, Tewari, Ambika, Angueyra, Chantal, Khodakhah, Kamran
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340526/
https://ncbi.nlm.nih.gov/pubmed/28198698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22775
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