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DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids

The number of children born since the origin of Assisted Reproductive Technologies (ART) exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been reported among ART-conceived infants, suggesting an epigenetic cost. We report the first whole-genome DNA methylation data...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Canovas, Sebastian, Ivanova, Elena, Romar, Raquel, García-Martínez, Soledad, Soriano-Úbeda, Cristina, García-Vázquez, Francisco A, Saadeh, Heba, Andrews, Simon, Kelsey, Gavin, Coy, Pilar
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340525/
https://ncbi.nlm.nih.gov/pubmed/28134613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23670
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