The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-associated bronchiolitis

Respiratory syncytial virus (RSV) causes significant infant morbidity and mortality. For decades severe RSV-induced disease was thought to result from an uncontrolled host response to viral replication, but recent work suggests that a strong innate immune response early in infection is protective. T...

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Bibliographic Details
Published in:PLoS One
Main Authors: Piedra, Felipe-Andrés, Mei, Minghua, Avadhanula, Vasanthi, Mehta, Reena, Aideyan, Letisha, Garofalo, Roberto P., Piedra, Pedro A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340370/
https://ncbi.nlm.nih.gov/pubmed/28267794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172953
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