Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis

Treatment options for metastatic renal cell carcinoma (RCC) are limited. In this study, we investigated impact of prostaglandin E2 (PGE2) receptor 4 (EP4) on RCC metastasis. We found that knockdown of EP4 in two RCC cell lines, ACHN and SN12C, does not affect xenograft tumor take or growth rate in m...

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Publicado en:Cancer Lett
Autores principales: Zhang, Yushan, Purayil, Hamsa Thayele, Black, Joseph B., Fetto, Francis, Lynch, Lauren D., Masannat, Jude N., Daaka, Yehia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340307/
https://ncbi.nlm.nih.gov/pubmed/28104442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.01.007
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