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New therapeutic strategies targeting D1-type dopamine receptors for neuropsychiatric disease

The neurotransmitter dopamine acts via two major classes of receptors, D1-type and D2-type. D1 receptors are highly expressed in the striatum and can also be found in the cerebral cortex. Here we review the role of D1 dopamine signaling in two major domains: L-DOPA-induced dyskinesias in Parkinson’s...

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Bibliographic Details
Published in:Front Biol (Beijing)
Main Authors: Kim, Young-Cho, Alberico, Stephanie L., Emmons, Eric, Narayanan, Nandakumar S.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340264/
https://ncbi.nlm.nih.gov/pubmed/28280503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-015-1360-4
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