Immune Escape via A Transient Gene Expression Program Enables Productive Replication of A Latent Pathogen

How type I/II interferons prevent periodic reemergence of latent pathogens in tissues of diverse cell-types remains unknown. Using homogenous neuron cultures latently-infected with herpes simplex virus-1, we show that extrinsic type I or II interferon act directly on neurons to induce unique gene ex...

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Publicat a:Cell Rep
Autors principals: Linderman, Jessica A., Kobayashi, Mariko, Rayannavar, Vinayak, Fak, John J., Darnell, Robert B., Chao, Moses V., Wilson, Angus C., Mohr, Ian
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340258/
https://ncbi.nlm.nih.gov/pubmed/28147283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.017
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