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Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer

Gemcitabine (GEM) and paclitaxel (PTX) are effective combination anticancer agents against non-small-cell lung cancer (NSCLC). At the present time, a main challenge of combination treatment is the precision of control that will maximize the combined effects. Here, we report a novel method to load GE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Liang, Yan, Tian, Baocheng, Zhang, Jing, Li, Keke, Wang, Lele, Han, Jingtian, Wu, Zimei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340246/
https://ncbi.nlm.nih.gov/pubmed/28280336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S121262
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