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Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages
Acidification of macrophage phagosomes serves an important bactericidal function. We show here that the redox-sensitive transient receptor potential (TRP) cation channel TRPM2 is expressed in the phagosomal membrane and regulates macrophage bactericidal activity through the activation of phagosomal...
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| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339887/ https://ncbi.nlm.nih.gov/pubmed/28082421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.196014 |
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