Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles

Alopecia areata (AA), a chronic, relapsing, hair-loss disorder, is considered to be a T cell-mediated autoimmune disease. It affects approximately 1.7% of the population, but its precise pathogenesis remains to be elucidated. Despite the recent attention focused on the roles of inflammasomes in the...

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Pubblicato in:Sci Rep
Autori principali: Shin, Jung-Min, Choi, Dae-Kyoung, Sohn, Kyung-Cheol, Kim, Soo-Yeon, Min Ha, Jeong, Ho Lee, Young, Im, Myung, Seo, Young-Joon, Deok Kim, Chang, Lee, Jeung-Hoon, Lee, Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339809/
https://ncbi.nlm.nih.gov/pubmed/28266599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44127
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