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The c-MYC Oncoprotein Is a Substrate of the Acetyltransferases hGCN5/PCAF and TIP60

The c-MYC oncoprotein functions as a sequence-specific transcription factor. The ability of c-MYC to activate transcription relies in part on the recruitment of cofactor complexes containing the histone acetyltransferases mammalian GCN5 (mGCN5)/PCAF and TIP60. In addition to acetylating histones, th...

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Autors principals: Patel, Jagruti H., Du, Yanping, Ard, Penny G., Phillips, Charles, Carella, Beth, Chen, Chi-Ju, Rakowski, Carrie, Chatterjee, Chandrima, Lieberman, Paul M., Lane, William S., Blobel, Gerd A., McMahon, Steven B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533976/
https://ncbi.nlm.nih.gov/pubmed/15572685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10826-10834.2004
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