Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods

Macaques play a central role in the development of human tuberculosis (TB) vaccines. Immune and challenge responses differ across macaque and human subpopulations. We used novel immunostimulation/immunodynamic modeling methods in a proof-of-concept study to determine which macaque subpopulations bes...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Vaccine Immunol
Hauptverfasser: Rhodes, Sophie J., Sarfas, Charlotte, Knight, Gwenan M., White, Andrew, Pathan, Ansar A., McShane, Helen, Evans, Thomas G., Fletcher, Helen, Sharpe, Sally, White, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339646/
https://ncbi.nlm.nih.gov/pubmed/28077441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00525-16
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