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Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells

Exposure to maternal cortisol plays a crucial role in fetal organogenesis. However, fetal overexposure to cortisol has been linked to a range of short- and long-term adverse outcomes. Normally, this is prevented by the expression of an enzyme in the placenta called 11-beta hydroxysteroid dehydrogena...

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Pubblicato in:Int J Cell Biol
Autori principali: Togher, Katie L., Kenny, Louise C., O'Keeffe, Gerard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339487/
https://ncbi.nlm.nih.gov/pubmed/28321257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6169310
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