Laddar...
Stable knockdown of CREB, HIF-1 and HIF-2 by replication-competent retroviruses abrogates the responses to hypoxia in hepatocellular carcinoma
The fast proliferation of tumor cells develops faster than the vasculature, resulting, in most malignant tumors, in generation of hypoxic regions. Hypoxia renders solid tumors resistant to radiation and chemotherapeutics while providing opportunities for tumor-selective therapies targeting tumor hyp...
Sparad:
| I publikationen: | Cancer Gene Ther |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2017
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339434/ https://ncbi.nlm.nih.gov/pubmed/27934882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2016.68 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|