Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation

AIMS: Some central nervous system pathogens express neuraminidase (NA) on their surfaces. In the rat brain, a single intracerebroventricular (ICV) injection of NA induces myelin vacuolation in axonal tracts. Here, we explore the nature, the time course, and the role of the complement system in this...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Neurol
Prif Awduron: Granados-Durán, Pablo, López-Ávalos, María Dolores, Cifuentes, Manuel, Pérez-Martín, Margarita, Fernández-Arjona, María del Mar, Hughes, Timothy R., Johnson, Krista, Morgan, B. Paul, Fernández-Llebrez, Pedro, Grondona, Jesús M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339270/
https://ncbi.nlm.nih.gov/pubmed/28326060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00078
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