PilY1 Promotes Legionella pneumophila Infection of Human Lung Tissue Explants and Contributes to Bacterial Adhesion, Host Cell Invasion, and Twitching Motility

Legionnaires' disease is an acute fibrinopurulent pneumonia. During infection Legionella pneumophila adheres to the alveolar lining and replicates intracellularly within recruited macrophages. Here we provide a sequence and domain composition analysis of the L. pneumophila PilY1 protein, which...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Hoppe, Julia, Ünal, Can M., Thiem, Stefanie, Grimpe, Louisa, Goldmann, Torsten, Gaßler, Nikolaus, Richter, Matthias, Shevchuk, Olga, Steinert, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339237/
https://ncbi.nlm.nih.gov/pubmed/28326293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00063
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