Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy

Hormone replacement therapy (HRT) affects the incidence and potential progression of colorectal cancer (CRC). As HRT primarily consists of estrone sulfate (E(1)S), understanding whether this conjugated estrogen is transported and metabolized in CRC will define its potential effect in this malignancy...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Gilligan, Lorna C., Gondal, Ali, Tang, Vivien, Hussain, Maryam T., Arvaniti, Anastasia, Hewitt, Anne-Marie, Foster, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339229/
https://ncbi.nlm.nih.gov/pubmed/28326039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00103
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