Glycocalyx Restricts Adenoviral Vector Access to Apical Receptors Expressed on Respiratory Epithelium In Vitro and In Vivo: Role for Tethered Mucins as Barriers to Lumenal Infection

Inefficient adenoviral vector (AdV)-mediated gene transfer to the ciliated respiratory epithelium has hindered gene transfer strategies for the treatment of cystic fibrosis lung disease. In part, the inefficiency is due to an absence of the coxsackie B and adenovirus type 2 and 5 receptor (CAR) from...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stonebraker, Jaclyn R., Wagner, Danielle, Lefensty, Robert W., Burns, Kimberlie, Gendler, Sandra J., Bergelson, Jeffrey M., Boucher, Richard C., O'Neal, Wanda K., Pickles, Raymond J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC533903/
https://ncbi.nlm.nih.gov/pubmed/15564484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13755-13768.2004
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker