Impact of caspase-1/11, -3, -7, or IL-1β/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease

Rabies virus is a highly neurovirulent RNA virus, which causes about 59000 deaths in humans each year. Previously, we described macrophage cytotoxicity upon infection with rabies virus. Here we examined the type of cell death and the role of specific caspases in cell death and disease development up...

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Publicat a:Cell Death Discov
Autors principals: Kip, E, Nazé, F, Suin, V, Vanden Berghe, T, Francart, A, Lamoral, S, Vandenabeele, P, Beyaert, R, Van Gucht, S, Kalai, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339016/
https://ncbi.nlm.nih.gov/pubmed/28280602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.12
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