Arenobufagin activates p53 to trigger esophageal squamous cell carcinoma cell apoptosis in vitro and in vivo

Esophageal squamous cell carcinoma (ESCC) is often diagnosed at late incurable stage and lacks effective treatment strategy. Bufadienolides are cardiotonic steroids isolated from the skin and parotid venom glands of the toad Bufo bufo gargarizans Cantor with novel anticancer activity. However, there...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Lv, Junhong, Lin, Shaohuan, Peng, Panli, Cai, Changqing, Deng, Jianming, Wang, Mingzhi, Li, Xuejun, Lin, Rongsheng, Lin, Yu, Fang, Ailing, Li, Qiling
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338965/
https://ncbi.nlm.nih.gov/pubmed/28280360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S104767
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