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Assessment of intratumor hypoxia by integrated (18)F-FDG PET / perfusion CT in a liver tumor model

OBJECTIVES: Hypoxia in solid tumors occurs when metabolic demands in tumor cells surpass the delivery of oxygenated blood. We hypothesize that the (18)F-fluorodeoxyglucose ((18)F-FDG) metabolism and tumor blood flow mismatch would correlate with tumor hypoxia. METHODS: Liver perfusion computed tomog...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, Yong, Stewart, Errol, Desjardins, Lise, Hadway, Jennifer, Morrison, Laura, Crukley, Cathie, Lee, Ting-Yim
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338799/
https://ncbi.nlm.nih.gov/pubmed/28264009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173016
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