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Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion
Cancer cell invasion from primary tumors is mediated by a complex interplay between cellular adhesions, actomyosin-driven contractility, and the physical characteristics of the extracellular matrix (ECM). Here, we incorporate a mechanochemical free-energy–based approach to elucidate how the two-way...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338523/ https://ncbi.nlm.nih.gov/pubmed/28196892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617037114 |
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