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Spectrin βV adaptive mutations and changes in subcellular location correlate with emergence of hair cell electromotility in mammalians

The remarkable hearing capacities of mammals arise from various evolutionary innovations. These include the cochlear outer hair cells and their singular feature, somatic electromotility, i.e., the ability of their cylindrical cell body to shorten and elongate upon cell depolarization and hyperpolari...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cortese, Matteo, Papal, Samantha, Pisciottano, Francisco, Elgoyhen, Ana Belén, Hardelin, Jean-Pierre, Petit, Christine, Franchini, Lucia Florencia, El-Amraoui, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338438/
https://ncbi.nlm.nih.gov/pubmed/28179572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618778114
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