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Single-Molecule Counting of Point Mutations by Transient DNA Binding
High-confidence detection of point mutations is important for disease diagnosis and clinical practice. Hybridization probes are extensively used, but are hindered by their poor single-nucleotide selectivity. Shortening the length of DNA hybridization probes weakens the stability of the probe-target...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338343/ https://ncbi.nlm.nih.gov/pubmed/28262827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43824 |
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