High glucose levels boost the aggressiveness of highly metastatic cholangiocarcinoma cells via O-GlcNAcylation

Increased glucose utilization is a feature of cancer cells to support cell survival, proliferation, and metastasis. An association between diabetes mellitus and cancer progression was previously demonstrated in cancers including cholangiocarcinoma (CCA). This study was aimed to determine the effects...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Phoomak, Chatchai, Vaeteewoottacharn, Kulthida, Silsirivanit, Atit, Saengboonmee, Charupong, Seubwai, Wunchana, Sawanyawisuth, Kanlayanee, Wongkham, Chaisiri, Wongkham, Sopit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338328/
https://ncbi.nlm.nih.gov/pubmed/28262738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43842
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