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Segmental duplications and evolutionary acquisition of UV damage response in the SPATA31 gene family of primates and humans

BACKGROUND: Segmental duplications are an abundant source for novel gene functions and evolutionary adaptations. This mechanism of generating novelty was very active during the evolution of primates particularly in the human lineage. Here, we characterize the evolution and function of the SPATA31 ge...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Bekpen, Cemalettin, Künzel, Sven, Xie, Chen, Eaaswarkhanth, Muthukrishnan, Lin, Yen-Lung, Gokcumen, Omer, Akdis, Cezmi A., Tautz, Diethard
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338094/
https://ncbi.nlm.nih.gov/pubmed/28264649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3595-8
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