The influence of population stratification on genetic markers associated with type 1 diabetes

Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were cor...

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Publicat a:Sci Rep
Autors principals: Gomes, Karla Fabiana Brasil, Santos, Aritânia Sousa, Semzezem, Cintia, Correia, Márcia Regina, Brito, Luciano Abreu, Ruiz, Marcelo Ortega, Fukui, Rosa Tsuneshiro, Matioli, Sergio Russo, Passos-Bueno, Maria Rita, Silva, Maria Elizabeth Rossi da
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338024/
https://ncbi.nlm.nih.gov/pubmed/28262800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43513
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