Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules

Endothelial exocytosis of Weibel–Palade body (WPB) is one of the first lines of defence against vascular injury. However, the mechanisms that control WPB exocytosis in the final stages (including the docking, priming and fusion of granules) are poorly understood. Here we show that the focal adhesion...

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發表在:Nat Commun
Main Authors: Han, Xiaofan, Li, Pin, Yang, Zhenghao, Huang, Xiaoshuai, Wei, Guoqin, Sun, Yujie, Kang, Xuya, Hu, Xueting, Deng, Qiuping, Chen, Liangyi, He, Aibin, Huo, Yingqing, Li, Dong, Betzig, Eric, Luo, Jincai
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338022/
https://ncbi.nlm.nih.gov/pubmed/28256511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14639
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