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Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain

It is well known that mutations in the gene coding for amyloid precursor protein are responsible for autosomal dominant forms of Alzheimer’s disease. Proteolytic processing of the protein leads to a number of metabolites including the amyloid beta peptide. Although brain amyloid precursor protein ex...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Puig, Kendra L., Brose, Stephen A., Zhou, Xudong, Sens, Mary A., Combs, Gerald F., Jensen, Michael D., Golovko, Mikhail Y., Combs, Colin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338020/
https://ncbi.nlm.nih.gov/pubmed/28262782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43725
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