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A 3D self-organizing multicellular epidermis model of barrier formation and hydration with realistic cell morphology based on EPISIM

The epidermis and the stratum corneum (SC) as its outermost layer have evolved to protect the body from evaporative water loss to the environment. To morphologically represent the extremely flattened cells of the SC - and thereby the epidermal barrier - in a multicellular computational model, we dev...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Sütterlin, Thomas, Tsingos, Erika, Bensaci, Jalil, Stamatas, Georgios N., Grabe, Niels
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338006/
https://ncbi.nlm.nih.gov/pubmed/28262741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43472
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