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Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway

Notch is a pleiotropic signaling family that has been implicated in pathogenesis of allergic airway diseases; however, the distinct function of individual Notch ligands remains elusive. We investigated whether Notch ligands, Jagged1 and DLL4, exert differential effects in OVA-induced allergic asthma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Miao-Tzu, Chen, Yi-Lien, Lien, Chia-I, Liu, Wei-Liang, Hsu, Li-Chung, Yagita, Hideo, Chiang, Bor-Luen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337933/
https://ncbi.nlm.nih.gov/pubmed/28262821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43535
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